RESULTS OF PROXIMAL TREATMENT OF PATIENTS WITH ORCHIECTOMY - RESISTANT PROSTATE CANCER ACCORDING TO THE DOCETAXEL - PREDNISOLONE REGIMEN

Anh Tú Đỗ1,, Thị Lệ Dương2
1 K hospital
2 HMU

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Abstract

Background: Combination of Docetaxel and Prednisone significantly prolongs overall survival. At the same time, the serum PSA response rate was also significantly higher. Purpose: To assess the outcomes of proximal treatment of patients with orchiectomy-resistant prostate cancer with the Docetaxel-Prednisolone regimen at K Hospital. Methods: Cross-sectional analysis of the results of close chemotherapy treatment of 38 patients with CRPC. Results: After 3 chemotherapy cycles, the objective response rate to treatment reached 24%, the disease control rate was 92%. PSA response rate was 53,6%. Median PSA progression-free survival was 6,0 months. The percentage of patients with pain relief was 66,7%. Conclusion: The results of Docetaxel-Prednisolone combined treatment were achieved an objective response rate of 24%, a disease control rate of 92%.

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References

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