THE CLINICAL MANIFESTATONS, LABORATORIES AND DEAFNESS COMPLICATIONS OF STREPTOCOCCUS SUIS IN NATIONAL HOSPITAL FOR TROPICAL DISEASES

Mạnh Hùng Thân1,2,, Đình Phú Vũ1
1 VNU Hanoi-University of Medicine and Pharmacy
2 Central Tropical Diseases Hospital

Main Article Content

Abstract

Streptococcus suis is one of the most common causes of bacteria meningitis in Vietnam. The S. suis meninigitis diseases had many sequelae, including irreversible deafness. Objectives: To describe the clinical manifestationss, laboratories and deaf complications in patients with S. suis meningitis. Methods: Prospective, collecting and analyzing clinical and laboratories data as well as the manifestations of deafness over time. Results: The S. Suis meningitis patients were generally men, the average mortality rate is 3.9%. The common clinical manifestations were Fever (100%), headache (92.8%), neck stiffness (90.1%), confusion (66.4%). There were 84.53% of patients with leukocytosis, the median CSF white blood cell count was 689 (TB/mm3), the protein was 2.72 g/L. Deaf complications occurred in 53.04% of patients, of which bilateral deafness accounted for 68.75%. 25.61% of patients recovered their deafness after 3 months. Conclusion: Fever, headache and altered consciousness are common symptoms. The S. suis meningitis patients had leukocytosis, mild coagulopathy. Deaf complications were found in 53.04%, the recovery was low.

Article Details

References

1. Vu Thi Lan Huong, Ngo Thi Hoa, Peter Horby, et al., (2014). Raw Pig Blood Consumption and Potential Risk for Streptococcus suis Infection, Vietnam. Emerging Infectious Diseases • http://www.cdc.gov/eid 20(11),1895-1898.
2. Hongjie Yu, Huaiqi Jing, Zhihai Chen, et al., (2006). Human Streptococcus suis Outbreak, Sichuan, China. Emerging Infectious Diseases • http://www.cdc.gov/eid, 2(6), 914 - 920.
3. Jacek Dutkiewicz, Jacek Sroka, Violetta Zając, et al., (2017). Streptococcus suis: a re-emerging pathogen associated with occupational exposure to pigs or pork products. Part I – Epidemiology. Annals of Agricultural and Environmental Medicine, 24(4), 683-695.
4. Nguyen Thi Hoang Mai, Ngo Thi Hoa, Tran Vu Thieu Nga, et al., (2008). Streptococcus suis Meningitis in Adults in Vietnam. Clinical Infectious Diseases, 46, 659–67.
5. Anusha van Samkar, Matthijs C. Brouwer, Constance Schultsz, et al., (2015). Streptococcus suis Meningitis: A Systematic Review and Meta-analysis. PLOS Neglected Tropical Diseases, 1-20.
6. Heiman F. L. Wertheim, Huyen Nguyen Nguyen, Walter Taylor, et al., (2009). Streptococcus suis, an Important Cause of Adult Bacterial Meningitis in Northern Vietnam. PLOS ONE, 4(6), e5973.
7. Wang, G., Y.L. Zeng, H.Y. Liu, et al., (2007). An outbreak of Streptococcus suis in Chengdu, China. Int J Clin Pract, 61(6), 1056-7.
8. Vu Thi Lan Huong, Ngo Ha, Nguyen Tien Huy, et al., (2014). Epidemiology, Clinical Manifestations, and Outcomes of Streptococcus suis Infection in Humans. Emerging Infectious Diseases Vol. 20, No. 7, 1105 - 1114.