EVALUATION OF TREATMENT ADHERENCE OF PATIENTS WITH RECURRENT BLEEDING ULCERATIVE COLITIS

Thị Hòa Trần1, Văn Cơ Lê2,, Ngọc Ánh Trần3
1 Ha Dong General Hospital
2 E Hospital
3 HMU

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Abstract

Research objective: To evaluate the treatment adherence of patients with recurrent bleeding ulcerative colitis at Hanoi Medical University Hospital and factors affecting the patient’s compliance rate. Methods: descriptive longitudinal follow-up, retrospective combined prospective study. Results: a study on 40 patients with recurrent bleeding ulcerative colitis at Hanoi Medical University Hospital. The rate of adherence to drug use reached 57.5%, non-adherence to drug use accounted for 42.5%. Causes of non-adherence to medication use: self-discontinuation in the absence of stool disorders (55%) and side effects (52.5%). Factors that significantly influence patient adherence to medication use such as education level, number of years of illness, number of medications, frequency of medication use, adverse reactions, knowledge of the disease, and especially relationship doctor-patient relationship. Conclusion: The effectiveness of the treatment depends on both the effect of the drug and the patient’s adherence to the treatment regimen. Therefore, it is very important to control the patient’s adherence to medication.

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References

1. Magro F, Gionchetti P, Eliakim R, et al. Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 1: Definitions, Diagnosis, Extra-intestinal Manifestations, Pregnancy, Cancer Surveillance, Surgery, and Ileo-anal Pouch Disorders. J Crohns Colitis. 2017;11(6):649-670. doi:10.1093/ecco-jcc/jjx008
2. Osterberg L, Blaschke T. Adherence to medication. N Engl J Med. 2005;353(5):487-497. doi:10.1056/NEJMra050100
3. Burkhart PV, Sabaté E. Adherence to long-term therapies: evidence for action. J Nurs Scholarsh Off Publ Sigma Theta Tau Int Honor Soc Nurs. 2003;35(3):207.
4. Brown MT, Bussell JK. Medication adherence: WHO cares? Mayo Clin Proc. 2011;86(4):304-314. doi:10.4065/mcp.2010.0575
5. Harbord M, Eliakim R, Bettenworth D, et al. Third European Evidence-based Consensus on Diagnosis and Management of Ulcerative Colitis. Part 2: Current Management. J Crohns Colitis. 2017;11(7):769-784. doi:10.1093/ecco-jcc/jjx009
6. Morisky DE, Ang A, Krousel-Wood M, Ward HJ. Predictive Validity of a Medication Adherence Measure in an Outpatient Setting. J Clin Hypertens. 2008;10(5):348-354. doi:10.1111/j.1751-7176.2008.07572.x
7. Tan X, Patel I, Chang J. Review of the four item Morisky Medication Adherence Scale (MMAS-4) and eight item Morisky Medication Adherence Scale (MMAS-8). Innov Pharm. 2014;5(3). doi:10.24926/iip.v5i3.347
8. Ridd MJ, Lewis G, Peters TJ, Salisbury C. Patient-Doctor Depth-of-Relationship Scale: Development and Validation. Ann Fam Med. 2011;9(6):538-545. doi:10.1370/afm.1322