GIÁ TRỊ DAO ĐỘNG XUNG KÝ TRONG CHẨN ĐOÁN HEN PHẾ QUẢN Ở TRẺ EM

Abstract

Backgrounds: Pediatric asthma, especially children <5 years old, is often difficult to diagnose, leading to a lack of prompt treatment and control. Impulse Oscillometry (IOS) is a method that can evaluate airway obstruction and recommend an early diagnosis. Objective: To determine the value of IOS in the diagnosis of asthma in children. Subjects and methods: A descriptive cross-sectional study was conducted on 104 children under 10 years old with suspected asthma symptoms who visited in the National Lung Hospital from January 2020 to August 2020. Results: There were 78 children diagnosed with asthma, the male/female (M/F) ratio was 2/1 (p = 0.003). There was a consistency between the diagnosis of asthma according to GINA and Decision No. 4888/QD-BYT by the Ministry of Health with the diagnosis recommendation based on bronchodilator therapy in IOS (kappa coefficient = 0.432). Value of R5, AX before bronchodilator test with AUC = 0,66 (p = 0,015), AUC = 0,67 (p = 0,009); And Value R5 change, Fres after test AUC = 0,783 (p = 0,000), %ChangeFres có AUC = 0,785 (p = 0,000) are mild valuable indicators for the diagnosis of asthma in children with cut-off was 0,88 kPa/L/s; 3,38 kPa/L, 18% and 15,5%.