ĐÁNH GIÁ CHỈ SỐ SỨC CĂNG THẤT TRÁI BẰNG SIÊU ÂM TIM ĐÁNH DẤU MÔ Ở BỆNH NHÂN SUY TIM CÓ TỔN THƯƠNG THẬN

Abstract

Objectives: To investigate the characteristics of left ventricular global longitudinal strain (GLS) and associations of GLS with clinical and laboratory characteristics in heart failure patients with chronic kidney disease. Subjects and methods: Cross-sectional descriptive study, analysis with comparison with controls. A total of 84 inpatient heart failure patients at the Department of Cardiology, 103 Military Hospital from January 2023 to June 2023, divided into 2 groups: the study group (42 heart failure patients with CKD) and the control group (42 heart failure patients without CKD). Patients underwent speckle tracking echocardiography to assess left ventricular GLS using a PHILIPS EPIQ7C ultrasound machine with QLAB 9.0 software installed. Results: Median age: Study group 77.2 ± 10.29; control group 64.3 ± 15.23. Average glomerular filtration rate of study group: 42.6 ± 10.97 ml/ph/1.73m2; Mean EF: Study group 52.2 ± 17.68%, control group 51.2 ± 19.87%. The GLS of the study group was not statistically significant compared to the control group (-11.23 ± 3.29% vs -11.43 ± 3.69%; p>0.05). GLS in patients with ischemic heart disease (-10.28 ± 3.12%) decreased statistically significantly compared with patients without IHD (-12.51 ± 3.13%); p<0.05. In the study group, the correlation between GLS and urea levels was inversely correlated (r = -0.333; p <0.05). There was no correlation between GLS and age, creatinine levels, log (NT-proBNP), red blood cell count, and hemoglobin (p>0.05); GLS correlated inversely with Dd (r = -0.375; p<0.05); but correlated with EDV (r=0.397; p<0.05) and ESV (r=0.428; p<0.05). Conclusion: In heart failure patients with CKD, GLS positively correlated with EDV and ESV but negatively correlated with Dd.