POLYPHARMACY AMONG OLDER PATIENTS AT OUTPATIENT DEPARTMENT, NINH BINH PROVINCIAL GENERAL HOSPITAL

Thị Hoài Giang Phạm1,, Thị Thu Hương Nguyễn2,3, Viết Lực Trần2,3, Thắng Phạm2,3,4
1 Ninh Binh Provincial General Hospital
2 Central Geriatric Hospital
3 HMU
4 Vietnam Geriatric Association

Main Article Content

Abstract

Objectives: To identify the prevalence and some associated factors of polypharmacy in older patients treated at the Outpatient Department, Ninh Binh Provincial General Hospital. Subjects and methods: Descriptive observational study on 370 older patients at the Outpatient Department, Ninh Binh Provincial General Hospital from August 2022 to July 2023. Polypharmacy was defined as the simultaneous use of 5 or more drugs in a day. Results: The mean age was 71.3±7.7 (year); females accounted for 50.8%. The rate of polypharmacy within one month before this visit was 41.4%. The rate of polypharmacy during this visit was 44.1%. The older the age, the higher the body mass index, the higher the polypharmacy rate, the difference was statistically significant with p < 0.05. The proportion of patients with frailty syndrome in the group with polypharmacy was statistically significantly higher than in the group without polypharmacy (p<0.05). Conclusion: The rate of polypharmacy in elderly out-patients treated at Ninh Binh Provincial General Hospital was quite high, and was associated with advanced age, high BMI, and frailty syndrome.

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References

1. Già Hóa Dân Số và Người Cao Tuổi ở Việt Nam. Thư viện trường đại học Y Hà Nội; 2021.
2. Hovstadius B, Petersson G. Factors leading to excessive polypharmacy. Clin Geriatr Med. 2012; 28(2): 159-172. doi:10.1016/j.cger.2012.01.001
3. Denneboom W, Dautzenberg MGH, Grol R, De Smet PAGM. Analysis of polypharmacy in older patients in primary care using a multidisciplinary expert panel. Br J Gen Pract. 2006;56(528):504-510.
4. Haider SI, Johnell K, Thorslund M, Fastbom J. Analysis of the association between polypharmacy and socioeconomic position among elderly aged > or =77 years in Sweden. Clin Ther. 2008; 30(2):419-427. doi: 10.1016/ j.clinthera. 2008.02.010
5. Shah BM, Hajjar ER. Polypharmacy, adverse drug reactions, and geriatric syndromes. Clin Geriatr Med. 2012; 28(2): 173-186. doi: 10.1016/ j.cger. 2012.01.002
6. Ahmed B, Nanji K, Mujeeb R, Patel MJ. Effects of polypharmacy on adverse drug reactions among geriatric outpatients at a tertiary care hospital in Karachi: a prospective cohort study. PLoS One. 2014; 9(11): e112133. doi: 10.1371/ journal.pone.01121337.
7. Ngô Thị Giang. Nhận Xét Tình Hình Sử Dụng Nhiều Thuốc ở Bệnh Nhân Điều Trị Nội Trú Tại Bệnh Viện Lão Khoa Trung Ương. Luận văn thạc sĩ. Trường Đại học y Hà Nội; 2015.
8. Phạm Thị Thu Hằng. Tình Hình Sử Dụng Nhiều Thuốc ở Bệnh Nhân Cao Tuổi Điều Trị Ngoại Trú Tại Bệnh Viện Lão Khoa Trung Ương. Luận văn bác sĩ chuyên khoa II. Trường Đại học y Hà Nội; 2017.