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Date Published: 24/11/2023
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DOI: https://doi.org/10.51298/vmj.v532i1.7343
Issue
Vol. 532 No. 1 (2023)
Section
Các bài báo
How to Cite
Nguyễn, T. D. D., & Vũ, H. T. (2023). THE EFFICACY OF IRINOTECAN MONOTHERAPY AS SECOND-LINE TREATMENT IN PATIENTS WITH ADVANCED GASTRIC CANCER. Vietnam Medical Journal, 532(1). https://doi.org/10.51298/vmj.v532i1.7343

THE EFFICACY OF IRINOTECAN MONOTHERAPY AS SECOND-LINE TREATMENT IN PATIENTS WITH ADVANCED GASTRIC CANCER

Thị Dương Dương Nguyễn1,, Hồng Thăng Vũ1,2
1 HMU
2 K Hospital

Main Article Content

Abstract

Objectives: To evaluate the efficacy of irinotecan monotherapy as second – line treatment in patients with advanced gastric cancer. Patiensand methods: Descriptive, retrospective, longitudinal case study of 43 patients with advanced gastric cancer refactory to or progressive after first – line chemotherapy, treatmented with irinotecan monotherapy as second-line treament from 01/2019 to 06/2023 at Vietnam’s National Cancer Hospital. Results: The mean age was 62,3 ± 11,7 (36-81); female/male ratio was 1/1,15. The overall response rate (ORR) was 18,6%, the DCR was 55,8%. The mean progression - free survival (PFS) was 4,0 ± 0,58 months, the median progression-free survival was 3,0 months. Conclusion: In patients with advanced gastric cancer, irinotecan  monotherapy is a resasonable second-line treatment option.

Article Details

Keywords

advanced gastric cancer, second-line treament, irionotecan monotherapy

References

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