CLINICAL & SUBCLINICAL CHARACTERISTICS OF PATIENTS HOSPITALIZED WITH SARS-COV-2 INFECTION IN FIELD HOSPITALS, VINH PHUC PROVINCE

Hong Trung Le 1, Anh Tuan Tran 1, Thi Nu Chu 1,, Van Truong Tru 2, Trung Kien Nguyen 3, Le Thuy Duong Nguy 3, Bao Ngoc Dang 4
1 Vinh Phuc Department of Health
2 Vinh Phuc General Hospital
3 Hanoi Medical University
4 College of Health Sciences, Vin University

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Abstract

Objectives: To describe the clinical features, laboratory findings, and treatment outcomes of 1040 cases diagnosed infected with SARS-CoV-2 at 3 Field Hospitals in Vinh Phuc Province. Subjects and method: A retrospective investigation was conducted on 1040 patients infected with SARS-CoV-2 and admitted to 3 field hospitals in Vinh Phuc Province, from May 2021 to December 2021. The diagnosis of SARS-CoV-2 infection was confirmed by portable RT-PCR assay. Results: A total of 1040 patients were hospitalized with SARS-CoV-2 infection, of which the majority of cases (91.5%) were classified as mild type at the time of admission. The median (IQR) age was 34 (18-49) years. It is noteworthy that only a minority of the patients presented with comorbidities such as hypertension (4.6%), diabetes (1.6%), COPD (0.2%), and CKD (0.1%). The proportion of unvaccinated COVID-19 patients was 63.5%, while only 0.9% received all 3 vaccine doses. The most common clinical feature on admission was cough (60.3%), followed by sore throat (27.3%), fever (11.3%), muscle fatigue (10%), headache (9.7%), and shortness of breath (9%). The majority of paraclinical indicators were within normal levels, except Lymphocytes. Straight Chest X-ray Scans showed a vast majority of patients (95.8%) had normal results, and few cases had abnormal laboratory parameters. Of all the patients, 313 (30.1%) cases received antiviral therapy, 96 (9.3%) cases received nasal oxygen therapy, 10 (0.96%) cases received HFNC/NIV, and only 3 (0.29%) cases received invasive mechanical ventilation. Regarding treatment outcomes, 828 (79.6%) patients were discharged with a mean hospital stay was 14.2±8.6 days, and only 1 (0.1%) case died. Conclusion: The present study reveals that most patients with mild COVID-19 were admitted to three Field Hospitals located in Vinh Phuc Province. Clinical manifestations primarily involved the respiratory system. The mean hospital stay duration was14.2±8.6 days. Of the COVID-19 patients, 828 (79.6%) cases were discharged from the hospital, while only 1 case died (0.1%).

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References

1. Argenziano M.G., Bruce S.L., Slater C.L., et al. (2020). Characterization and clinical course of 1000 patients with coronavirus disease 2019 in New York: retrospective case series. The BMJ, 369, m1996.
2. Centers for Disease Control and Prevention (2020). Coronavirus Disease 2019 (COVID-19). .
3. Liao Y., Feng Y., Wang B., et al. (2020). Clinical characteristics and prognostic factors of COVID-19 patients progression to severe: a retrospective, observational study. Aging, 12(19), 18853–18865.
4. Ministry of Health (2021). Decision No. 3416/QD-BYT Guidelines on diagnosis and treatment for COVID-19 caused by the novel Coronavirus (SARS-CoV-2).
5. Thach P.N. (2021), COVID-19 Monograph for Healthcare Professional, Medical Publishing House.
6. World Health Organization (2021). Coronavirus (COVID-19) Dashboard. .
7. Zhan T., Liu M., Tang Y., et al. (2020). Retrospective analysis of clinical characteristics of 405 patients with COVID-19. J Int Med Res, 48(8), 0300060520949039.
8. Zhang J., Dong X., Cao Y., et al. (2020). Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China. Allergy, 75(7), 1730–1741.