SURVEY ON CONCENTRATION OF PLASMA ACID URIC IN TYPE 2 DIABETIC MELLITUS PATIENTS WITH CHRONIC NEPHROPATHY

Đào Bùi Quý Quyền, Bùi Hữu Hoàng, Lê Việt Thắng

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Abstract

Objectives:To determine of plasma acid uric (AU)levels in type 2 diabetic mellitus (DM) with chronic nephropathy (CN). Subjects and methods: Cross-sectional study on 156 subjects including 98 patients diagnosed type 2 DM with CN and 58 patients without CN. Plasma AU levels were quantified by enzyme in all the patients. Results: The median plasma AU concentration in the DM group with CN was 423.55 (333.6-524.35)µmol/L, higher than the group without CN was 341.15 (297.2-408.95)µmol/L, p<0.001. The proportion of serum AU increase inDM patients with CN was 60.2% higher than that of the DM group without CN of 29.3%, p<0.001. The AU concentration in group of DM patients with CN and ≥ 60 years old; CN stage 3-5; with complications others, was higher than of the one without the above characteristics, p<0.05. Conclusion: Increased AU is common in patients with type 2 diabetic mellitus with chronic nephropathy.

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References

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