ANGIOGRAPHIC SEVERITY OF CORONARY ARTERY DISEASE IN PATIENTS WITH NON-ST ELEVATION MYOCARDIAL INFARCTION AND FRAGMENTED QRS

Thị Thanh Bình Đào 1,, Phan Thu Loan Trương2
1 Pham Ngoc Thach University of Medicine
2 People's Hospital 115 - City. Ho Chi Minh

Main Article Content

Abstract

Fragmented QRS (fQRS) complexes are novel electrocardiographic signals, which reflect myocardial conduction delays in patients with coronary artery disease (CAD). The fQRS complexes in 12 lead ECG may develop in the background of acute coronary syndrome (ACS). This study was aimed to evaluate the angiographic severity of CAD among non-ST ACS patients having fQRS in the ECG. Methods: This cross-sectional observational study was conducted at the Nhan Dan Gia Dinh hospital from Jan 2023 to June 2023. All patients underwent 12-lead surface ECG at admission before coronary angiogram (CAG) and were divided in two groups according to presence or absence of fQRS complex. After CAG, severity of CAD was assessed and compared by quantity and degree of coronary stenosis between two groups. Results: This study included 99 non-ST ACS patients who underwent invasive coronary angiography (CAG). fQRS was present in 35 patients (35.4%) and 64 patients (64.6%) in non fQRS group. Among fQRS patient group, the highest percentage had triple vessels. And those had a significantly higher frequency than non fQRS group (65.7% vs 42.2%, p=0.04). With fQRS group, the most severe 1 vessel stenosis rate is 97.1%. Conclusion: This study revealed that presence of fQRS in ECG is associated with more severity of CAD and the patient should be managed and targeted for aggressive management.

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References

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