MỘT SỐ ĐẶC ĐIỂM LÂM SÀNG VÀ CẬN LÂM SÀNG CỦA BỆNH NHÂN TUYỆT LẠP BẠCH CẦU HẠT DO THUỐC KHÁNG GIÁP TỔNG HỢP TẠI BỆNH VIỆN CHỢ RẪY

Abstract

Objective: To investigate clinical and laboratory characteristics of patients diagnosed with antithyroid- induced agranulocytosis in Cho Ray hospital. Subjects: Data of 40 patients with antithyroid- induced agranulocytosis were collected. Method: Retrospective study. Results: Median age of studied population was 40,5 with the majority were females treated with Methimazole. Major symptoms were fever and sore throat. Median granulocytes at admission were 65/µL and hyperthyroidism was not well controlled in most of the patients. Median time for granulocyte recovery was 6 days. ConclusionsAntithyroid-induced agranulocytosis is a rare but lethal complication, therefore, predictive biomarker for this adverse reaction need to be studied and identified.