SURVEY ON CONCENTRATION OF PLASMA HS-CRP IN TYPE 2 DIABETIC MELLITUS PATIENTS WITH CHRONIC NEPHROPATHY

Bùi Hữu Hoàng, Đào Bùi Quý Quyền, Lê Việt Thắng

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Abstract

Objectives: To determine of plasma hs-CRP levels in type 2 diabetic mellitus (DM) with chronic nephropathy (CN). Subjects and Methods: Cross-sectional study on 156 subjects including 98 patients diagnosed type 2 DM with CN and 58 patients without CN. Plasma hs-CRP levels were quantified by immunoassay turbidity in al the patients. Results: The median plasma hs-CRP concentration in the DM group with CN was 2.34 (1.31-3.96) mg/L, higher than the group without CN was 1.7 (0.78-3.08) mg/L, p<0.05. The proportion of serum hs-CRP increase inDM patients with CN was 17.3% higher than that of the DM group without CN of 1.7%, p<0.05. The hs-CRP concentration in group of DM patients with CN and lipid disorders; poor blood glucose control; with complications others, was higher than of the one without the above characteristics, p<0.05. Conclusion: Kidney damage in type 2 DM patients increases the plasma hs-CRP concentration.

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References

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