THE CHARACTERISTICS OF THE AXILLARY LYMPH NODE METASTASIS IN INVASIVE LOBULAR BREAST CARCINOMA
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Abstract
This report aims to assess the rate of lymph node metastasis and the correlation between lymph node metastasis and some risk factors in invasive lobular breast carcinoma. A descriptive cross-sectional study was conducted on 98 patients with invasive lobular breast carcinoma at the Department of Pathology - Cytology, National Cancer Hospital from January 2019 to April 2023. The study results show that the rate of lymph node metastasis was 48,0%. The factors associated with the increased risk of lymph node metastasis were large tumor size, high tumor grade, the presence of lymphovascular invasion, ER expression, some molecular subtypes (triple-negative breast cancer, luminal B-like breast cancer, and HER2-enriched breast cancer) (p < 0,05). The results of this study hope to aid patient selection for axillary lymph node dissection and improve patient counseling.
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Keywords
lymph node metastasis, risk factors, invasive lobular breast carcinoma
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