EFFICACY OF DUAL OOCYTE MATURATION REGIMEN AND OOCYTE MATURATION BY HCG ALONE ON POOR OVARIAN RESPONSE

Thị Hằng Đoàn1,, Ngọc Lan Đỗ1, Thế Sơn Trịnh1, Minh Phương Nguyễn1
1 Military Medical University

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Abstract

Objective: To compare the results of the number of retrieved oocytes, the number of mature oocytes and the number of embryos between the two groups that received dual-trigger with human Chorionic Gonadotropin (hCG) plus GnRH-agonist (GnRHa) and only hCG trigger for final oocyte maturation on  poor ovarian response in IVF cycles. Methods: The study was carried out on 64 patients with poor ovarian response undergoing IVF at the Military Institute of clinical Embryology and Histology, Vietnam Military Medical University, divided into two groups. Results: Number of mature oocytes (3.31±1.15 vs 2.47±1.48, p=0.013), number of fertilized oocytes (2.63±0.98 vs 1.86±1.39, p=0.015), number of day 3 embryos (2.62±1.04 vs 1.84±1.42, p=0.015), number of day 5 embryos (1.97±1.00 vs 1.06±1.27, p=0.002). Conclusion: Dual oocyte maturation regimen was shown to increase the number of retrieved oocytes, the number of mature oocytes and the number of embryos obtained compared with using hCG alone in the poor ovarian response group.

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References

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