CORRELATION BETWEEN MOTOR SCALE AND DELAYED GASTRIC EMPTYING IN PARKINSON DISEASE

Trần Thanh Hùng, Vũ Anh Nhị, Nguyễn Xuân Cảnh

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Abstract

Background: Parkinson’s disease (PD) is the second most common neurodegenerative disease after Alzheimer disease. Delayed gastric emptying could be impactful in treatment of PD patients. Objectives: To investigate the correlation between motor scale and delayed gastric emptying in PD. Methods: A cross-sectional study was conducted on PD patients with their informed consent. Patients were evaluated on their motor complications using UPDRS and were also received radionuclide gastric emptying study using solid meal. The analysis was done using R version 4.0.3. Results: Seventy-two patients were included in our study with 73.6% were female. There were 72.2% patients with at least one motor complications. The delayed gastric emptying rate was 45.8%. Patient with delayed gastric emptying had statistically higher score on rigidity, extrapyramidal symptoms, postural instability (p< 0.01) and lower score on postural tremor of the hands (p=0.027) compared to patient without delayed gastric emptying using Kruskall-Wallis test. Conclusions: Motor symptoms of Parkinson disease need to be recognized by clinicians to evaluate delayed gastric emptying in PD patients.

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References

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