MÔ TẢ TÁC DỤNG KHÔNG MONG MUỐN CỦA KÍCH THÍCH TỪ XUYÊN SỌ Ở NGƯỜI BỆNH TÂM THẦN PHÂN LIỆT THỂ PARANOID ĐIỀU TRỊ NỘI TRÚ

Abstract

Research objective: To describe of undesirable effects of transcranial magnetic stimulation in inpatient paranoid schizophrenia. Subjects: 104 patients diagnosed with schizophrenia according to ICD 10. Methods: Clinical intervention on 104 patients with paranoid schizophrenia, in which 33 patients received drug intervention with sufficient transcranial magnetic stimulation, 32 patients received drug intervention with insufficient transcranial magnetic stimulation. at the position of the left parietal temporal cortex (90% MT, 1 Hz, pulse sequence 1200s, rest time between 2 pulses 0s, 19'59 minutes a treatment session, 12 sessions, 2 times a day 5 hours apart, 5 hours apart) and 39 patients taking the drug alone. Results: There were 33.3% had undesirable effects in which the most common was head and neck muscle twitching (23.5%), followed by toothache (20.6%), transient headache (18.2%), finger twitching. (12.2%), pain at the site of contact (12.1%). There was 1 patient had an undesirable effect of hearing loss (3%), 1 patient had neck pain (3%), 1 patient had dizziness (3%). No patient experienced convulsions, skin burns, difficulty concentrating and breathing, syncope, tingling, transient euphoria and other undesirable effects. Study subjects experienced the most unwanted effects of head and neck muscle twitching in the first 4 treatment sessions, the highest rate in session 1 (7.6%), the highest rate in session 1 (3%), the highest rate of toothache session 4 (9.3%), highest transient headache session 2 (7.8%). The adverse effects mainly distributed in the age group 20-44 years old, the highest in this group were the undesirable effects of toothache and transient headache, both 57.1%, but there was a difference between different symptoms, low most in the group under 20 years old and a few in the group over 45 years old. Conclusion: Adverse effects are quite common but mild occurs during transcranial magnetic stimulation, of which the most common is head and neck muscle twitching, followed by toothache, transient headache, and muscle twitching. finger, pain at the place of contact. There was 1 patient had an undesirable effect of hearing loss, 1 patient had neck pain, 1 patient had dizziness. No patient experienced convulsions, skin burns, difficulty concentrating and breathing, syncope, tingling, transient euphoria and other undesirable effects. The undesirable effects were most common in the first sessions, then gradually decreased in the following sessions, distributed relatively evenly in both sexes, however, the symptoms were head and neck muscle twitching, finger twitching, toothache. , transient headache, neck pain more than men, symptoms of hearing loss, dizziness are common in women, tend to focus mainly on the age group 20-44 years old and do not experience any serious unwanted effects.