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Date Published: 02/01/2024
Abstract Views: 717
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DOI: https://doi.org/10.51298/vmj.v533i1.7796
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Vol. 533 No. 1 (2023)
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Trần , T. B. H. ., & Trần , T. V. . (2024). COMPARISON OF THE 2021 (WITHOUT RACE ADJUSTMENT) AND 2009 CKD-EPI FOR ESTIMATED GLOMERULAR FILTRATION. Vietnam Medical Journal, 533(1). https://doi.org/10.51298/vmj.v533i1.7796

COMPARISON OF THE 2021 (WITHOUT RACE ADJUSTMENT) AND 2009 CKD-EPI FOR ESTIMATED GLOMERULAR FILTRATION

Thị Bích Hương Trần , Thành Vinh Trần

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Abstract

Our goals were (1) To compare the 2021 and 2009 CKD-EPI equations, (2) To inspect the new equation on the stage of chronic kidney disease (CKD). Methods: a cross – sectional retrospective study. Results  We had 537 participants (100 healthy medical students, 437 CKD patients. Median age of 30, 243 (45,3%) male. The median of 2021 CKD-EPI eGFRcr increased 0,22 (IQR 0,016-13,9) ml/min/1,73 m2 compared to the 2009 CKD-EPI one. The median of difference between 2 eGFRcr was 1,2% (IQR 0,02-39,4)%. In which, 52,6% cases had the 2021 CKD-EPI eGFRcr higher, 38.3% no change and 9,1% lower than the 2009 CKD-EPI eGFRcr. There was 127 (23,6%) cases change the CKD stage by using the  new equation, in which, mainly 69 cases (12,8%) from G2 to G1. No case of the 2021 CKD-EPI eGFRcr changes to the more severe stage. The number of patients with eGFRcr <60ml/min/1.73 decreased 4.8% from 236/538 (43.9%) in the 2009 CKD-EPI equation to 210/537 (39,1%) patients in the new equation. Conclusions: The new equation of 2021 CKD-EPI, removed adjustment for race, increased the value of eGFRcr compared to the previous 2009 CKD-EPI, and influenced to the stage of CKD by increasing the number of G2 to G1 and decreased the number of patients with eGFR < 60ml/min/1.73

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