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Date Published: 05/01/2024
Abstract Views: 319
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DOI: https://doi.org/10.51298/vmj.v533i1B.7813
Issue
Vol. 533 No. 1B (2023)
Section
Các bài báo
How to Cite
Nguyễn , T. T. H. ., Đỗ , H. N., Đỗ , A. T. ., & Hoàng , D. H. . (2024). THE EFFECT OF CONCURRENT CHEMORADIOTHERAPY FOLLOWED BY VIDL CHEMOTHERAPY IN EXTRANODAL NK/T-CELL LYMPHOMA, NASAL TYPE IN K. Vietnam Medical Journal, 533(1B). https://doi.org/10.51298/vmj.v533i1B.7813

THE EFFECT OF CONCURRENT CHEMORADIOTHERAPY FOLLOWED BY VIDL CHEMOTHERAPY IN EXTRANODAL NK/T-CELL LYMPHOMA, NASAL TYPE IN K

Thị Thu Hường Nguyễn , Huyền Nga Đỗ , Anh Tú Đỗ , Dương Huy Hoàng

Main Article Content

Abstract

We conducted performed a descriptive study on a series of cases to evaluate the effectiveness of VIDL regimen after concurrent chemoradiaotherapy with cisplatin in stage IE/IIE nasal extranodal T/NK cell lymphoma. Concurrent chemoradiotherapy yielded a 66,67% complete response rate, 26,67% partial response rate; common adverse effects were dermatitis and oral mucositis. After concurrent chemoradiotherapy, VIDL showed 86,67% complete response rate, 13,33% partial response rate. Hematologic toxicity was frequent during VIDL chemotherapy (grades III/IV 13,33%), no treatment-relates mortality was observed. PFS and OS at 1 year were 100%. In conclusion, concurrent chemoradiaotherapy followed by VIDL is a feasible treatment for stages IE/IIE nasal extranodal T/NK cell lymphoma.

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References

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