NHẬN XÉT TRIỆU CHỨNG LÂM SÀNG, CẬN LÂM SÀNG VÀ KẾT QUẢ ĐIỀU TRỊ TRÊN 08 BỆNH NHÂN LAO MANG THAI BẰNG THỤ TINH TRONG ỐNG NGHIỆM TẠI KHOA NỘI TỔNG HỢP, BỆNH VIỆN PHỔI TRUNG ƯƠNG

Abstract

Objective: To assess the clinical and laboratory characteristics, diagnosis, and treatment outcomes of tuberculosis in IVF pregnant patients. Subjects and Methods: This retrospective study was conducted in the General Internal Medicine Department of the National Lung Hospital from January 2021 to March 2023. A total of 8 patients were included in the study. Results: The average age of the patients was approximately 31.6 ± 7.0 years old. All patients had fallopian tube obstruction or partial obstruction. The time from IVF embryo transfer to the onset of symptoms was 90.6 ± 21.5 days. The average time between symptom onset and X-ray examination was 23.4 ± 5.1 days. The mean white blood cell count in cerebrospinal fluid was 448.1 ± 716.1, with a higher percentage of neutrophils (50.8 ± 15.5%) compared to lymphocytes (45.5 ± 15.0%). Genexpert and Bactec culture of sputum showed a high positive rate in cerebrospinal fluid, with 75% (6) and 87.5% (7) respectively. Seven patients (87.5%) were diagnosed with mycobacterium tuberculosis. However, only 3 infants were born (37.5%), all of whom were premature and underweight. Conclusion: Genital tuberculosis is a risk factor when undergoing IVF, leading to more severe disease outcomes. Pregnant women with tuberculosis tend to experience miscarriages, premature births, and low birth weight infants.