KHẢO SÁT NỒNG ĐỘ MICROALBUMIN, CREATININ VÀ CHỈ SỐ MICROALBUMIN/CREATININ Ở MẪU NƯỚC TIỂU NGẪU NHIÊN Ở BỆNH NHÂN ĐÁI THÁO ĐƯỜNG TYPE 2

Abstract

Background: Diabetes is a common chronic metabolic disorder, causing many complications and often severe prognosis. Microalbuminuria and microalbumin/creatinine index are harbingers of progressive renal disease and cardiovascular complications in patients with diabetes mellitus. Objectives: To investigate microalbumin, creatinin concentrations and microalbumin/creatinin index in random urine samples of patients with type 2 diabetes at Ca Mau Provincial General Hospital in the year 2019 - 2020. Subjects and methods: A cross-sectional descriptive study was conducted on 245 samples, collected at the Department of Endocrinology, Ca Mau Province General Hospital from 3/2019 to 8/2020. Tests for the following indicators: albumin, creatinine, glucose, HbA1c on blood samples and microalbumin, creatinine on random urine samples in the study subjects, were performed on the Beckman Coulter AU680 biochemical analyzer. Result: Microalbumin, Creatinine concentrations and ACR index in random urine samples of patients with type 2 diabetes have median respectively are 24,0 mg/L; 52,6 mmol/L and 0,73 mg/mmol. Conclusion: ACR in random urine samples helps early diagnosis of Diabetic nephropathy. Especially, early diagnosis of Diabetic nephropathy in patients with type 2 diabetes > 5 years, HbA1c ≥ 7%, age > 50 years old.