SARCOPENIA VÀ MỘT SỐ YẾU TỐ LIÊN QUAN Ở BỆNH NHÂN VIÊM CỘT SỐNG DÍNH KHỚP

Abstract

Patients with ankylosing spondylitis (AS) who have sarcopenia, a muscular condition, may experience a variety of negative issues, including a decreased quality of life and an elevated mortality risk. Objective: To describe the characteristics of Sarcopenia and to survey some related factors in AS patients at Hanoi Medical University Hospital. Subjects and methods: A descriptive cross-sectional study was conducted on 26 AS patients at the Hanoi Medical University Hospital between February 2023 and August 2023. The diagnosis of Sarcopenia and AS is based on the criteria of the 2019 Asian Working Group for Sarcopenia (AWGS 2019) and 1984 Modified New York criteria, respectively. Results: The proportion of patients with pre-sarcopenia, sarcopenia and severe sarcopenia in AS patients was 53.85%, 30.77% and 11.54%, respectively. A lower BMI and a higher hs-CRP level were found in the group of patients with sarcopenia than in the other groups. Compared to groups with low disease activity and normal nutritional status, the prevalence of sarcopenia in the very high disease activity and the malnutrition groups, respectively, was 17 and 13.3 times greater, with a p-value of 0.05. Conclusion: Sarcopenia was estimated to influence up to more over one-third of AS patients at Hanoi Medical University Hospital. In order to reduce the risk of sarcopenia, good disease control and nutritional condition in AS patients are absolutely essential.