CURRENT STATUS OF NON RESPONSE TO INFLIXIMAB IN ANKYLOSING SPONDYLITIS MANAGEMENT

Thị Như Hoa Nguyễn, Duy Hiệp Nguyễn

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Abstract

Aims: To determine the prevalence of non - response to  infliximab and other factors related to the non – response to infliximab in Ankylosing spondylitis patients. Subjects and methods: longitudinal, descriptive study in patients received infliximab in Ankylosing spondylitis at Bach Mai Hospital from August 2018 to August 2022. Results: In this study of 74 patients (87,8% male, 29,4 ± 11,8 years of age) ankylosing spondylitis patients in the study, which included primary lack of response PLR (5; 6,8%), secondary lack of response SLR (26; 35,1%) and responders (43; 58,1%). The secondary non-responders had a greater prevalence of medication non-adherence than the responders to infliximab. Conclusions: Non - response to  infliximab in Ankylosing spondylitis patients: 41,9%. The secondary non-responders had a greater prevalence of medication non-adherence than the responders to infliximab.

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References

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