ĐẶC ĐIỂM VIÊM PHỔI CẦN HỖ TRỢ HÔ HẤP Ở TRẺ NHIỄM SARS-COV-2 TẠI BỆNH VIỆN NHI ĐỒNG 2 NĂM 2021-2022

Abstract

Objectives: To describe the clinical, laboratory and treatment characteristics of pneumonia requiring respiratory support in children infected with SARS-CoV-2. Methods: A case series of 127 children infected with SARS-CoV-2 diagnosed pneumonia requiring respiratory support at the Children's Hospital No2 from January 1^st, 2021 to December 31^st, 2022. Results: Among 127 children infected with SARS-CoV-2 who develop pneumonia and require respiratory support, children 60 months and older accounted for the highest proportion (48%). The male/female ratio was 1.7/1. Children with underlying diseases accounted for 40.2% and obesity 16.7%. The spectrum of SARS-CoV-2 infection severity included moderate diseases (22.8%), severe diseases (56.7%), and critical diseases (20.5%).The most common clinical symptoms and signs were chest indrawing (92,1%), fever (85%), cough (81.1%), and tachypnea (63.8%). The median SpO2 level was 86.9%. No pulmonary rales recorded 70.1%. There were 34.6% of children whose lymphocyte count decreased with age. The elevations in D-dimer, Ferritin, CRP, AST and ALT occurred in 79.3%, 75.3%, 43.7%, 18.1% and 7.9% of children, respectively. The most common lesions on chest X-ray were pulmonary consolidation (41.7%), alveolar infiltrates (33.9%), and interstitial infiltrates (22.8%).The methods of respiratory support included nasal cannula (31.5%), NCPAP (41.7%), and mechanical ventilation (26.8%). The median time requiring respiratory support was 6.8 days. There were 24 children who died (18.9%). Conclusions: Children infected with SARS-CoV-2 who develop pneumonia and require respiratory support have a high fatality rate.