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Date Published: 15/01/2024
Abstract Views: 68
Views PDF: 69
DOI: https://doi.org/10.51298/vmj.v534i1.8092
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Vol. 534 No. 1 (2024)
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Các bài báo
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Nguyễn, T. N. H. ., & Nguyễn, D. H. . (2024). CURRENT STATUS OF NON RESPONSE TO ADALIMUMAB IN ANKYLOSING SPONDYLITIS MANAGEMENT. Vietnam Medical Journal, 534(1). https://doi.org/10.51298/vmj.v534i1.8092

CURRENT STATUS OF NON RESPONSE TO ADALIMUMAB IN ANKYLOSING SPONDYLITIS MANAGEMENT

Thị Như Hoa Nguyễn, Duy Hiệp Nguyễn

Main Article Content

Abstract

Aims: To determine the prevalence of non - response to  adalimumab and other factors related to the non – response to adalimumab in Ankylosing spondylitis patients. Subjects and methods: longitudinal, descriptive study in patients received adalimumab in Ankylosing spondylitis at Bach Mai Hospital from August 2018 to August 2022. Results: In this study of 35 ankylosing spondylitis patients (80,0% male, 27,9 ± 11,8 years of age), the percentages of primary lack of response (PLR) was 8,6% and secondary lack of response (SLR) - 14,3% respectively. Conclusions: The percentage of non - response to adalimumab in our Ankylosing spondylitis patients was 22,9%. No correlation was found between non - response to adalimumab and male sex, older age, disease duration, peripheral arthritis, HLA B27, ASDAS-CRP, medication non-adherence, concomitant methotrexat of ankylosing spondylitis patients under adalimumab.

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References

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