CLINICAL CHARACTERISTICS, ENDOSCOPIC IMAGES AND RESULTS OF ENDOSCOPIC TREATMENT FOR PATIENTS WITH UPPER GASTROINTESTNAL BLEEDING DUO TO GASTRIC-DUODENAL ULCER

Văn Khiên Vũ , Minh Thắng Dương , Xuân Hùng Trịnh , Tuấn Sơn Nguyễn

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Abstract

Objective: The present study airm to compare hemoclips + adrenaline injection with hemoclips alone for the treatment of bleeding gastroduodenal ulcer. Subject and method: 150 patients with major stigmata of gastroduodenal ulcer bleeding were randomly assigned to receive hemoclips + adrenalin (n = 75) and hemoclips alone (n =75). All patients are resident treatment, clinical examination, laboratory, and upper gastrointestinal endoscopy. The primary end point of rebleeding rate and end point of innitial hemostasis need for surgery and mortality were compared between the two groups. Results: Initial hemostasis was achieved in 75/75 (100%) of the group hemoclips + adrenalin and 68/75 (90.7%) of the hemoclips alone (p < 0.05). The rate of recurrent gastrointestinal bleeding, blood transfusions, surgical rate of the group hemoclips + adrenalin 1/10.000 were lower not significant compared to patients with hemoclips alone. However, the hospital stays of the group hemoclips + adrenalin 1/10.000 were shorter significant compared to patients with hemoclips alone (p<0,05). Conclusion: Combination therapy (clip + adrenalin) for better efficiency than clip alone.

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References

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