FACTORS RELATED TO INTRACEREBRAL HEMATOMA IN PATIENTS WITH SUBARACHNOID HEMORRHAGE DUE TO RUPTURED CEREBRAL ANEURYSM

Văn Ninh Dương , Anh Tuấn Nguyễn , Quốc Chính Lương , Hữu Thông Trần

Main Article Content

Abstract

Descriptive observational study to determine some clinical and paraclinical parameters related to subarachnoid hemorrhage with brain parenchymal hematoma from August 2021 to July 2023 at Bach Mai hospital. Among Of the 330 patients, 189 (57.3%) were female and the median age was 58 years (IQR: 50–65). Intracerebral hematoma appeared in 20 % (66/330) of patients with subarachnoid hemorrhage. There is a difference between the two groups with brain parenchymal hematoma and without Intracerebral hematoma: initial symptoms: (headache, loss of consciousness), focal neurological signs: (hemiplegia, Glasgow score), aneurysm location (middle cerebral artery, posterior communicating artery), severity of subarachnoid bleeding (World Federation of Neurosurgery classification levels IV, V). Multivariate regression analysis showed factors associated with Intracerebral hematoma in patients with subarachnoid hemorrhage: hemiplegia (OR: 5.641; 95% CI: 2.358 to 13.489; p<0.001), hematoma subdural (OR: 5.310; 95% CI: 1.043 to 27.039; p = 0.044), severity classified according to the World Federation of Neurosurgeons (WFNS) grade IV (OR: 4.218 95% CI: 1.295 to 9.088 p < 0.001), grade V (OR: 7.615 95 % CI: 2.752 to 21.072 p < 0.001) and ruptured middle cerebral artery aneurysm (OR: 5.218; 95% CI: 1.958 to 10.602; p < 0.001).

Article Details

References

1. Feigin VL, Stark BA, Johnson CO, et al. Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. The Lancet Neurology. 2021;20(10):795-820. doi:10.1016/S1474-4422(21)00252-0
2. Hoh BL, Ko NU, Amin-Hanjani S, et al. 2023 Guideline for the Management of Patients With Aneurysmal Subarachnoid Hemorrhage: A Guideline From the American Heart Association/American Stroke Association. Stroke. 2023;54(7): e314-e370. doi: .1161/ STR. 0000000000000436
3. Darkwah Oppong M, Skowronek V, Pierscianek D, et al. Aneurysmal intracerebral hematoma: Risk factors and surgical treatment decisions. Clin Neurol Neurosurg. 2018;173:1-7. doi:10.1016/j.clineuro.2018.07.014
4. Tokuda Y, Inagawa T, Katoh Y, Kumano K, Ohbayashi N, Yoshioka H. Intracerebral hematoma in patients with ruptured cerebral aneurysms. Surg Neurol. 1995;43(3):272-277. doi: 10.1016/0090-3019(95)80013-7
5. Platz J, Güresir E, Wagner M, Seifert V, Konczalla J. Increased risk of delayed cerebral ischemia in subarachnoid hemorrhage patients with additional intracerebral hematoma. J Neurosurg. 2017;126(2):504-510. doi:10.3171/ 2015.12. JNS151563
6. Wan A, Jaja BNR, Schweizer TA, Macdonald RL, on behalf of the SAHIT collaboration. Clinical characteristics and outcome of aneurysmal subarachnoid hemorrhage with intracerebral hematoma. J Neurosurg. 2016;125(6):1344-1351. doi:10.3171/2015.10.JNS151036
7. Güresir E, Beck J, Vatter H, et al. Subarachnoid hemorrhage and intracerebral hematoma: incidence, prognostic factors, and outcome. Neurosurgery. 2008;63(6):1088-1093; discussion 1093-1094. doi: 10.1227/ 01.NEU. 0000335170.76722.B9
8. Bruder M, Schuss P, Berkefeld J, et al. Subarachnoid hemorrhage and intracerebral hematoma caused by aneurysms of the anterior circulation: influence of hematoma localization on outcome. Neurosurg Rev. 2014;37(4):653-659. doi:10.1007/s10143-014-0560-8
9. Hauerberg J, Eskesen V, Rosenørn J. The prognostic significance of intracerebral haematoma as shown on CT scanning after aneurysmal subarachnoid haemorrhage. Br J Neurosurg. 1994;8(3): 333-339. doi: 10.3109/ 02688699409029622