SARCOPENIA VÀ MỘT SỐ YẾU TỐ LIÊN QUAN Ở NGƯỜI BỆNH THẬN MẠN CHƯA ĐIỀU TRỊ THAY THẾ THẬN

Abstract

Sarcopenia is highly prevalent in patients with chronic kidney disease (CKD) and is associated with an increased risk of morbidity, mortality, and cardiovascular complications. Objective: Describe the prevalence of sarcopenia and its associated factors in non-dialysis CKD patients at Bach Mai Hospital. Method: A cross-sectional study was conducted on 156 patients diagnosed with sarcopenia according to the criteria of the Asian Working Group for Sarcopenia (2019) and CKD according to the Kidney Disease: Improving Global Outcomes (KDIGO) criteria (2012). Results: The prevalence of sarcopenia in CKD patients was 29.49%. Sarcopenia was observed in all stages of CKD, with the highest prevalence being 58.4% in stage 5 and the lowest being 13.3% in stage 1. CKD patients in stages 3b-5 had lower handgrip strength compared to those in stages 1-3a (p<0.05). Multivariate linear regression analysis showed that advanced age, anemia, and the presence of multiple comorbidities were factors associated with an increased risk of sarcopenia in CKD patients (p<0.001). Conclusion: Sarcopenia is a common condition in non-dialysis CKD patients and is present in all stages of CKD, particularly in elderly patients with severe renal impairment, anemia, and multiple comorbidities. Therefore, early diagnosis of sarcopenia in CKD patients is crucial to minimize adverse outcomes in those who have not yet initiated renal replacement therapy.