KHẢO SÁT MẬT ĐỘ XƯƠNG VÀ MỘT SỐ YẾU TỐ LIÊN QUAN Ở BỆNH NHÂN BỆNH PHỔI TẮC NGHẼN MẠN TÍNH ĐIỀU TRỊ NGOẠI TRÚ TẠI BỆNH VIỆN BẠCH MAI

Abstract

Patients with chronic obstructive pulmonary disease are at higher risk of osteoporosis than healthy people because bone loss occurs over a course of years. There are many factors involved in the pathogenesis of osteoporosis in patients with chronic obstructive pulmonary disease. Objective: Determine the rate of osteoporosis and some related factors in chronic obstructive pulmonary disease patients treated as outpatients at Bach Mai hospital. Research subjects and methods: Cross-sectional, prospective, descriptive study conducted on 50 patients with chronic obstructive pulmonary disease treated as outpatients at Bach Mai hospital. Results: The rate of osteoporosis in the lumbar spine was 52%, decreased bone density in the lumbar spine was 38%. At the femoral neck, the rate of osteoporosis and reduced bone density is 34% and 52%. The overall rate of osteoporosis is 60% and decreased BMD is 32%. Several factors related to osteoporosis were identified in the study including female gender (p=0.033< 0.05), low BMI (<18.5 kg/m2) (p=0.035<0.05), inhaled corticosteroid use. (ICS) (p=0.01<0.05), COPD subtype (p=0.005<0.05). Conclusion: COPD patients have a relatively high risk of osteoporosis (60%), this condition is related to a number of factors such as female gender, low BMI, ICS use, COPD subtype and is not related to age or smoking, and disease duration.