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Date Published: 07/08/2021
Abstract Views: 136
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DOI: https://doi.org/10.51298/vmj.v504i1.822
Issue
Vol. 504 No. 1 (2021)
Section
Các bài báo
How to Cite
Minh Tùng, N. ., Văn Ba, N. ., & Đăng Tôn, N. . (2021). MITOCHONDRIAL NADH DEHYDROGENASE SUBUNIT 5 AND SUBUNIT 6 GENE POLYMORPHISMS IN GIARAI AND EDE ETHNIC PEOPLE LIVING IN THE CENTRAL HIGHLANDS. Vietnam Medical Journal, 504(1). https://doi.org/10.51298/vmj.v504i1.822

MITOCHONDRIAL NADH DEHYDROGENASE SUBUNIT 5 AND SUBUNIT 6 GENE POLYMORPHISMS IN GIARAI AND EDE ETHNIC PEOPLE LIVING IN THE CENTRAL HIGHLANDS

Nguyễn Minh Tùng1,, Nguyễn Văn Ba2, Nguyễn Đăng Tôn3
1 Vietnam Military Medical Academy
2 Military Hospital 103
3 Institute of Genome Research, Vietnam Academy of Science and Technology

Main Article Content

Abstract

Objective:To determined the mitochondrial NADH dehydrogenase subunit 5 and NADH dehydrogenase subunit 6 gene polymorphisms in GiaRai and Ede ethnic people living in central highlands. Subjects and methods: 54 peripheral blood samples of healthy people from Giarai and Ede ethnic groups were extracted DNA, amplified ND5, ND6 genes by PCR, purified DNA, and sequenced automatically. Then, ND5 and ND6 gene sequences were analyzed and compared with standard sequences using specialized software, comparing ND5, ND6 polymorphisms with polymorphisms published on MITOMAP. Results: ND5, ND6 sequences and the mitochondrial NADH dehydrogenase subunit 5 and NADH dehydrogenase subunit 6  gene polymorphisms in GiaRai and Ede ethnic people living in central highlands were identified. Conclusions: This study provided data on ND5 and ND6 gene sequence and polymorphisms in GiaRai and Ede ethnic groups living in the Central Highlands.

Article Details

Keywords

Polymorphisms, ND5, ND6, Gia Rai, Ede, Central Highlands

References

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