MỘT SỐ ĐẶC ĐIỂM NHIỄM VIÊM GAN VIRUS B, C TRÊN BỆNH NHÂN CẮT GAN DO HCC TẠI BỆNH VIỆN K

Abstract

Objective: Describe some characteristics of hepatitis B and C virus infection in patients undergoing liver resection due to HCC at national cancer Hospital. Research subjects and methods: A retrospective descriptive study on 228 patients undergoing surgery. Hepatectomy due to HCC (with post-operative pathological diagnosis of HCC) included (47 cases of right anterior sectionectomy, 33 cases of right posterior sectionectomy, 38 cases of central hepatectomy and 110 cases of right hepatectomy) at the Department of Hepatobiliary and Pancreatic Surgery - K Hospital from 2019 to 2023. Research results: Male: female ratio: 9.4:1. Average age: 56.1. Types of hepatectomy included 47 anterior segment hepatectomies (20.6%), 33 posterior segment hepatectomies (14.5%), 38 central hepatectomies (16.7%), and 110 right hepatectomies (48.2%).  History of hepatitis B and C: 105 cases (46.1%). Tests for HBsAg and HCV were positive: 183 cases (182 cases of single infection and 1 case of co-infection with hepatitis B and C), accounting for 80.3%. AFP rate < 20 ng/ml was 77 cases (33.8%), from 20 - 400 ng/ml was 58 cases (25.4%) and > 400 ng/ml was 93 cases (40.8%); The group of patients with hepatitis B, C and hepatitis B and C co-infection had 25.4% AFP within normal limits. Conclusion: Hepatitis B and C are high - risk factors in HCC surgery patients, accounting for 80.3%. However, the history of hepatitis B and C only accounts for 46.1%, proving that hepatitis screening is still limited.