EVALUATING THE LONG-TERM IMPACT OF THE ANTIMICROBIAL STEWARDSHIP PROGRAM AT THE HOSPITAL FOR TROPICAL DISEASES: A SIMULATION STUDY

Thị Hải Yến Nguyễn, Ngọc Cẩm Tiên Phùng, Thị Hồng Nguyên Trần , Đặng Tú Nguyên Lê, Quốc Bảo Mai , Thanh Ngọc Quyên Dương , Phương Thảo Huỳnh , Văn Vĩnh Châu Nguyễn

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Abstract

Objective: Evaluating the long-term impact of the antimicrobial stewardship program (ASP) at the Hospital for Tropical Diseases in Ho Chi Minh City by simulation modeling. Subjects and methods: The object of this study is the Antimicrobial Stewardship program at Ho Chi Minh City Hospital for Tropical Diseases in the period 2016 – 2018 (pASP) and 2018 – 2020 (nASP). Results: The results from the simulation modeling showed that there was a difference in LOT per 1.000 patient days (LOT/1.000 PD) and DOT per 1.000 patient days (LOT/1.000 PD) from the two programs; however, this difference was no more than 1 unit. The nASP was more effective in the number of infectious periods and antimicrobial switching. The average cost of treatment per case in the nASP period was lower than that of the pASP stage (14.393.915 VND compared to 15.954.576 VND) and the total cost of treatment of the cases, if nASP was implemented for 5 years, will save 38.902.432.416 VND compared to pASP. Conclusion: The study has opened up the direction of applying simulation modeling to compare and select optimal stewardship options in hospital management in general and stewardship, use of antibiotics in particular.

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References

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