KHẢO SÁT TÌNH HÌNH CHẨN ĐOÁN VÀ ĐIỀU TRỊ LOÃNG XƯƠNG Ở BỆNH NHÂN BỆNH PHỔI TẮC NGHẼN MẠN TÍNH CAO TUỔI

Abstract

Objectives: To investigate the diagnosis and treatment of osteoporosis in elderly patients with chronic obstructive pulmonary disease (COPD). Methods: A descriptive cross-sectional study was conducted on 107 patients aged ≥ 60 at the Pulmonary Function Testing Department of the University Medical Center in Ho Chi Minh City, from December 2022 to May 2023, diagnosed with the 2022 Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines. Results: The prevalence of osteoporosis in patients with COPD was 31,8%, with the rate in diagnosis of 41,2% and the rate in treatment of 38,2%. Bisphosphonate drugs used were alendronate, ibandronate, and zoledronic acid. Factors such as older age (OR = 4,44; p = 0,043), female gender (OR = 8,85; p = 0,025), low body weight (OR = 7,28; p = 0,011), and glucocorticoid use (OR = 6,07; p = 0,002) increased the risk of osteoporosis in COPD patients, while physical exercise acted as a protective factor, reducing the risk (OR = 0,08; p = 0,006). Conclusion: The prevalence of osteoporosis in COPD patients was 31,8%, the rates of  the diagnosis and  treatment were 41,2% and 38,2%, respectively. Risk factors of osteoporosis in COPD patients were older age, female gender, and glucocorticoid use, while exercise proved to be a protective factor in reducing risk in these patients.