ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG CỦA BỆNH NHÂN VIÊM TỤY CẤP CÓ TỔN THƯƠNG THẬN CẤP

Abstract

Aim: Describe clinical and paraclinical characteristics in patients with acute kidney injury following acute pancreatitis. Methods: Cross-sectional study of 219 patients with acute pancreatitis divided into 2 groups: 51 patients with acute kidney injury following acute pancreatitis (AP-AKI)  and 168 patients acute pancreatitis without acute kidney injury (AP-non-AKI). Result: - There are 51/219 AP-AKI. The rate of financial intervention in stages 1, 2 and 3 is 47.1%; 33.3% and 19.6%. Men accounted for a higher proportion than women in both the study groups of AP-AKI (88.2% men vs. 11.8% of women) and AP non AKI (80.4% of men vs. 19.6 women). - The AP-AKI had higher rates of abdominal distension, respiratory rate, SpO₂, temperature, prothrombin rate (seconds), INR and lower prothrombin rate (%) with statistical significance (p<0.05) compared to the group of AP non AKI. Blood biochemistry: Glucose, Urea, Creatinine LDH, GOT, Bilirubin, CRP and Lactate of the group of AP-AKI had a statistically significant higher median value than the group of AP non AKI. Albumin, Sodium, Potassium, Chlorine, Calcium TP and glomerular filtration rate of the group of patients with AP-AKI were statistically significantly lower than the group AP non AKI. The group of AP-AKI had lower pH, pCO₂, HCO₃^- and higher pO₂ than the group of AP-non-AKI, the difference was statistically significant with p < 0.01; The P/F index between the 2 study groups did not have a statistically significant difference. - Abdominal CT scan, Balthazar E were the highest rate in both study groups, the difference according to the Balthazar scale and CTSI score between the 2 groups was statistically significant, the rate of acute necrotizing pancreatitis was not different significant between the 2 groups. The scores of APACHE II, SOFA, IMRIE, BISAP, MARSHAL of the AP-AKI were statistically significantly higher than the AP non AKI. - There were 3/51 (5.9%) had poor outcome. Conclusion: Acute kidney injury is a dangerous complication of acute pancreatitis.