ĐẶC ĐIỂM DI CĂN HẠCH TRONG UNG THƯ ĐẠI TRÀNG PHẢI ĐƯỢC PHẪU THUẬT TRIỆT CĂN TẠI BỆNH VIỆN K

Abstract

Objective: To determine the rate of lymph node metastasis and evaluate the relationship between tumor characteristics and lymph node metastasis in right colon cancer. Methods: Prospective research of 48 cases diagnosed with right colon cancer (including the cecum, ascending colon, hepatic flexure and right transverse colon), underwent radical surgery at K hospital from February 2023 - August 2023. Then, the lymph nodes will be dissected in stages and histopathologically evaluated separately for each level. Determine histopathology (adenocarcinoma or mucinous adenocarcinoma), invasion (T1, T2, T3, T4), differentiation (high, moderate, poor), and stage of disease after surgery. The relationship between the patient’s characteristics and the tumor’s characteristics with lymph node metastasis will be evaluated. The data are collected and processed by SPSS 20 software. Results: In the 48 patients studied, the common age was 50-70 (60.4%), the average age was 58.85 ± 12.89, male/female ratio was 1.35; The most common histopathology type is adenocarcinoma (79.2%), moderately differentiated (75.0%). The rate of lymph node metastasis is 29.2% and 6,25% cases metastases at the third level. This difference was not statistically significant, p=0.09. There is a relationship between tumor invasion and lymph node metastasis rate and increased lymph node metastasis rate in cases of T3 and T4 tumors, the difference is not statistically significant, p = 0.163. There is no difference between the lymph node metastasis rate and tumor differentiation, p = 1.000.