TỈ LỆ TRÀO NGƯỢC DẠ DÀY THỰC QUẢN TRÊN BỆNH NHÂN BỆNH PHỔI TẮC NGHẼN MẠN TÍNH VÀ CÁC YẾU TỐ LIÊN QUAN

Abstract

Gastroesophageal reflux disease is a common comorbidity in patients with chronic obstructive pulmonary disease. The objective of the study was to determine the rate of GERD in COPD patients, the clinical characteristics of COPD in patients with and without GERD, and to identify factors related to the occurrence of GERD in COPD patients. This is a cross-sectional study of 209 COPD patients aged 40 years and older at the respiratory outpatient clinic of Nguyen Tri Phuong hospital from February 2023 to August 2023. We found that the prevalence of GERD in COPD patients was 32,50%, COPD patients with GERD had a higher average age (67,50 vs. 64,54, p = 0,018). There are 4 independent factors related to the occurrence of GERD in COPD patients including age, history of peptic ulcers disease, diabetes mellitus and frequent exacerbations with ORs of 1,07; 7,56; 2,43 and 2,52 respectively. To conclude, nearly one-third of patients with COPD have GERD. Early awareness of GERD and factors associated with its occurrence in COPD patients will help clinicians better recognize and manage the coexistence of GERD and COPD.