SURVEY OF CARDIO-ANKLE VASCULAR INDEX AND RELATIONSHIP WITH CLINICAL , SUBCLINICAL CHARACTERISTICS IN PATIENTS TREATING WITH MAINTENANCE HEMODIALYSIS

Nguyễn Văn Tuyên1,, Bùi Mỹ Hạnh2, Lê Việt Thắng3
1 Duc Giang General Hospital, Hanoi
2 Hanoi Medical University
3 Military Hospital 103, Vietnam Military Medical University

Main Article Content

Abstract

Objective: To investigate Cardio-Ankle Vascular Index (CAVI) and its relationship with some clinical and subclinical characteristics of patients with regular hemodialysis. Subjects and methods: A cross-sectional descriptive study of 111 maintenance hemodialysis patients and 88 normal people of the same age and sex. All subjects were measured CAVI index. Results: The average CAVI index in hemodialysis patients was 9.96 ± 2.14, higher than that of normal people (8.14 ± 0.59), p<0.001. Ratio of increased CAVI compared with the control group was 66.7%. The patients with age ≥ 60 years old; hemodialysis time ≥ 5 years; loss of residual renal function; diabetes mellitus; hypertension had mean CAVI and/or ratio of increase CAVI was higher than those of the patients without the above characteristics, p<0.05. The CAVI has a positive correlation with the duration of hemodialysis, r = 0.247, p < 0.01. Conclusion: Increased CAVI is common in hemodialysis patients and it related to old age, prolonged duration of hemodialysis, loss of residual renal function, diabetic mellitus and hypertension.

Article Details

References

1. Chen J, Budoff MJ, Reilly MP, et al. (2017). Coronary Artery Calcification and Risk of Cardiovascular Disease and Death Among Patients With Chronic Kidney Disease. JAMA Cardiol. 2(6):635-643.
2. Thomas R., Kanso A., Sedor J.R. (2008). Chronic kidney disease and its complications. Prim Care, 35(2): 329 – 32.
3. Ichihara A, Yamashita N, Takemitsu T, et al. (2008). Cardio-ankle vascular index and ankle pulse wave velocity as a marker of arterial fibrosis in kidney failure treated by hemodialysis. Am J Kidney Dis, 52(5), 947-955.
4. Kato A, Takita T, Furuhashi M, et al. (2012). Brachial-Ankle Pulse Wave Velocity and the Cardio-AnkleVascular Index as a Predictor of Cardiovascular Outcomesin Patients on Regular Hemodialysis. Therapeutic Apheresis and Dialysis 16 (3): 232-241.
5. Takenaka T, Hoshi H, Kato N, et al (2008). Cardio-Ankle Vascular Index to Screen Cardiovascular Diseases in Patients with End-Stage Renal Diseases. J Atheroscler Thromb 15: 339-44.
6. Jeznach-Steinhagen A, Słotwiński R, Szczygieł B. (2007). Malnutrition, inflammation, atherosclerosis in hemodialysis patients. Rocz Panstw Zakl Hig. 58(1):83-8.
7. Nagayama D., Saiki A., Endo K., Yamaguchi T., et al. (2010). Improvement of cardio-ankle vascular index by glimepiride in type 2 diabetic patients. Int J Clin Pract, 64(13), pp. 1796-1801.
8. Takafumi Okura, Sanae Wanatabe, et al. (2007). Relationship betwen cardio ankle vascular index (CAVI) and carotid atherosclerosis in patients with essential hypertension. Hypertens Res 30 (4): 335-340.