SỰ BIẾN ĐỔI ĐIỆN CƠ BỀ MẶT VÀ NỒNG ĐỘ MỘT SỐ CYTOKINE HUYẾT TƯƠNG DƯỚI TÁC DỤNG CỦA THỦY CHÂM CHẾ PHẨM CHỨA NỌC ONG APITOXIN TRÊN BỆNH NHÂN ĐAU THẮT LƯNG DO THOÁI HÓA CỘT SỐNG

Abstract

Objectives: To evaluate changes in shifted parameters of sEMG and serum concentrations of some cytokine in patients with spinal degeneration induced low back pain treated by Apitoxin acupuncture. Subjects and methods: 100 patients with spinal degeneration induced low back pain were divided into two groups. They were treated by Electro-acupuncture following apitoxin bee venom acupuncture at dose 0.0025 mg/kg (Apitoxin bee venom group) or saline acupuncture (control group). sEMG and serum concentrations of IL-1β and TNF-α were measured before and at the 15^th day of treatments. Results: There were significant decreases in mean intensity of muscles relax (baseline) and mean time to peak while there were increases in mean maximum intensity of muscle contraction (peak) and mean muscle contraction energy (PeakArea) after 15 treatment days in compared to these before treatments. There were significant differences in the above indexes between two groups after treatments. Furthermore, there were no significant differences in serum concentrations of IL-1β and TNF-α between before and after treatments in both groups. In conclusion: Apitoxin bee venom acupunctures induced significant changes in shifted parameter of (sEMG) but not serum concentrations of IL-1β and TNF-α.