MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN KẾT QUẢ ĐIỀU TRỊ CỦA BỆNH NHÂN NHƯỢC CƠ SAU PHẪU THUẬT CẮT TUYẾN ỨC

Abstract

Objective: We analyzed some factors related to the treatment outcomes of patients with myasthenia gravis after thymectomy. Subjects and methods: The cross-sectional descriptive study was conducted from March 2021 to August 2023 on 66 myasthenia gravis patients who had thymectomy at Bach Mai Hospital. Results: Patients with mild disease stages (I, IIA) according to the Ossermann classification after thymectomy have a higher rate of improvement than patients with moderate and severe stages (IIB, III, IV): OR = 164.50 (95%CI: 15.23 – 708.50). The patient hasn't had symptoms of difficulty swallowing or breathing before surgery is a favorable factor for improved results after surgery with an OR of 9.80 (95% CI: 1.20 - 80.35) and an OR of 5, respectively (95% CI: 1.31 – 19.07). A complete removal of the thymoma and surrounding fatty tissue and patient compliance with treatment resulted in better improvement after thymectomy (p<0.05). Factors such as gender, age, and thymus pathology have not been found to be related to the results of surgical treatment. Conclusion: Patients with mild clinical stage myasthenia gravis after thymectomy will have better clinical improvement than moderate and severe patients