COMPARING THE RESULTS OF SIMULTANEOUS PORTAL AND HEPATIC VEIN EMBOLIZATION USING A TRANS-JUGULAR APPROACH WITH A TRANSHEPATIC APPROACH

Văn Sỹ Thân, Thanh Dũng Lê, Minh Thông Phạm

Main Article Content

Abstract

The study aimed to compare the results of using transjugular approach versus transhepatic approach in liver venous deprivation (LVD) procedures for liver hypertrophy before hepatectomy. From January 2021 to November 2023, 62 patients with hepatocellular carcinoma (HCC) (median age of 52.5 years) received LVD to increase the future liver remnant (FLR) before hepatectomy, of which 13 cases used the tranjugular approach and 49 cases used the transhepatic approach. After LVD, all patients obtained FLR enough for surgery. FLR volumes before and after LVD in the transjugular group were 390.0 ml and 630.0 ml, respectively, (p < 0.001) compared to 400.3 ml and 639.0 ml, respectively, (p < 0.001) in the transhepatic group. The ratio of FLR to the standard liver volume before and after LVD in the transjugular group was 31.8% and 48.4%, respectively (p < 0.001), compared to 32.7% and 48.7% in the transhepatic group. The rate of liver hypertrophy in the two groups was 55.2% and 54.0%, respectively, p = 0.355. One case in the transhepatic group presented transient liver failure after LVD. The study results show that LVD is a safe, effective and feasible procedure to increase FLR volume before hepatectomy in HCC patients. There is no significant statistical difference in the safety and effectiveness of liver hypertrophy after LVD when using transjugular or transhepatic approach

Article Details

References

1. Schreckenbach T, Liese J, Bechstein WO, Moench C. Posthepatectomy liver failure. Dig Surg. 2012;29(1):79-85.
2. Cieslak KP, Runge JH, Heger M, Stoker J, Bennink RJ, Van Gulik TM. New perspectives in the assessment of future remnant liver. Dig Surg. 2015;31(4-5):255-268.
3. Guiu B, Quenet F, Panaro F, et al. Liver venous deprivation versus portal vein embolization before major hepatectomy: future liver remnant volumetric and functional changes. Hepatobiliary Surg Nutr. 2020;9(5):564.
4. Le Roy B, Gallon A, Cauchy F, et al. Combined biembolization induces higher hypertrophy than portal vein embolization before major liver resection. HPB. 2020;22(2):298-305.
5. Laurent C, Fernandez B, Marichez A, et al. Radiological simultaneous portohepatic vein embolization (RASPE) before major hepatectomy: a better way to optimize liver hypertrophy compared to portal vein embolization. Ann Surg. 2020; 272(2):199-205.
6. Kobayashi K, Yamaguchi T, Denys A, et al. Liver venous deprivation compared to portal vein embolization to induce hypertrophy of the future liver remnant before major hepatectomy: A single center experience. Surgery. 2020;167(6):917-923.
7. Della Corte A, Santangelo D, Augello L, et al. Single-Center Retrospective Study Comparing Double Vein Embolization via a Trans-Jugular Approach with Liver Venous Deprivation via a Trans-Hepatic Approach. Cardiovasc Intervent Radiol. Published online September 13, 2023. doi:10.1007/s00270-023-03538-3
8. Camelo R, Luz JH, Gomes FV, Coimbra E, Costa NV, Bilhim T. Portal vein embolization with pva and coils before major hepatectomy: single-center retrospective analysis in sixty-four patients. J Oncol. 2019;2019:4634309.