COMPARISION OF EFFECTS ON HEMODYNAMICS, RESPIRATION, AND SOME SIDES EFFECTS OF GRANISETRONE AND ONDASETRONE FOR PREVENTING NAUSEA AND VOMITING IN WOMEN UNDERGOING SPINAL ANESTHESIA FOR CESAREAN SECTION

Xuân Huỳnh Đặng, Đức Lam Nguyễn, Thị Ngọc Vân Lương, Thị Hải Nguyễn

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Abstract

Objects: To compare of the effects on hemodynamics, respiration, and some sides effects of granisetrone and ondasetrone for preventing nausea and vomiting in women undergoing spinal anesthesia for cesarean section. Methods: RCT study on 100 patients divided into two groups. Group 1: Using Granisetrone 1mg injection before spinal anesthesia. Group 2: Using Ondansetrone 1mg injection before spinal anesthesia. Results: Granisetrone does not affect hemodynamics and respiration or the incidence of sides effects on pregnant women compared to ondasetron. Conclusion: Granisetrone used to prevent nausea and vomiting in women undergoing spinal anesthesia for C-section does not affected the pregnant women’s respiration and hemodynamics, does not cause arrhythmia and does not increase rate or severity of sides effects compared to ondasetrone.

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References

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