COMPARISON OF CLINICAL AXILLARY ULTRASOUND RESULTS VERSUS POST-OPERATIVE PATHOLOGY RESULTS IN BREAST CANCER SURGERY IN K HOSPITAL

Hồng Khoa Phạm, Tiến Đạt Mai, Nguyên Tuấn Trần

Main Article Content

Abstract

Background: Breast cancer is considered as a systemic disease, especially in lymph nodes metastases stage, when treatment is multimodality. Axillary ultrasound is a crucial pre-operative workup for evaluation stages and first-choice treatment. In addition, ultrasound also plays an important role in choosing patient for sentinel-lymph nodes biopsy in early breast cancer. Objectives: This study evaluate rates of lymph nodes metastasis in patients with normal axillary lymph nodes ultrasound results by comparing ultrasound results and post-operative pathology results. In contemporary evaluating related factors forecasting lymph nodes metastasis in operable-breast cancer. Methods: Description of cross-sectional series of patients diagnosed as operable breast cancer which lymph nodes are normal or suspected of metastatis in ultrasound. Treatment is mastectomy or breast-conserving surgery with lymph node dissection, at Optimal Care Unit in K hospital from December 2022 to July 2023. Results: 105 breast cancer patients are diagnosed as operable stages, treated with mastectomy or breast-conserving surgery, compared results of clinical axillary ultrasound versus post-operative pathology results. In which there are 3 patients diagnosed as intraductal carcinoma and 102 patients are invasive carcinoma. In 102 cases, rates of T1 and T2 stage are 55.9% and 44.1%, respectively. The average age is 52.25. The majority of tumor histopathology is invasive ductal carcinoma, 88 cases accounted for 86.7%. The average number of lymph nodes dissection is 15.2, at most of 29 and at least of 6. Lymph nodes metastasis represents in 30 patients, accounted for 28.6%. The rate of lymph nodes metastasis in normal clinical axillary lymph nodes ultrasound is 21.7%, appeared as average of 1.4 lymph nodes. That number in suspected ultrasound group are 41.7% and 2.73 lymph nodes. Conclusions: The study shows that ultrasound is a non-invasive and effective method in evaluation of preoperative lymph node staging. The study also recommend perform fine needle aspiration if ultrasound detect positive lymph nodes, before sentinel lymph nodes biopsy procedure. There are differences in rate and number of lymph nodes metastasis between normal and suspected ultrasound results, statistical significance.

Article Details

References

1. Cuamani-Mitznahuatl G, Rocha-González HI, Flores-Balcázar CH, et al. Effectiveness of ultrasound in the detection of axillary metastasis in patients with breast cancer without clinical evidence of axillary disease: Clinical impact. Rev Senol Patol Mamar. 2021; 34(3):140-147. doi:10.1016/j.senol.2020.07.007.
2. García Fernández A, Fraile M, Giménez N, et al. Use of Axillary Ultrasound, Ultrasound-Fine Needle Aspiration Biopsy and Magnetic Resonance Imaging in the Preoperative Triage of Breast Cancer Patients Considered for Sentinel Node Biopsy. Ultrasound in Medicine & Biology. 2011; 37(1):16-22.doi:10.1016/j.ultrasmedbio.2010. 10.011.
3. Al-Hilli Z, Wilkerson A. Breast Surgery: Management of Postoperative Complications Following Operations for Breast Cancer. Surgical Clinics of North America. 2021; 101(5):845-863. doi:10.1016/j.suc.2021.06.014.
4. Deurloo EE, Tanis PJ, Gilhuijs KGA, et al. Reduction in the number of sentinel lymph node procedures by preoperative ultrasonography of the axilla in breast cancer. European Journal of Cancer. 2003; 39(8):1068-1073. doi:10.1016/ S0959-8049(02)00748-7.
5. Lê HQ, Đào MT. đánh giá tình trạng di căn hạch nách và một số yếu tố liên quan trên bệnh nhân ung thư vú giai đoạn I – IIIA tại bệnh viện K. VMJ. 2022; 512(2). doi:10.51298/ vmj.v512i2. 2273.
6. Huỳnh QK, Phan VHH, Nguyễn VK. Đánh giá di căn hạch nách trong ung thư vú giai đoạn I-II (ct1-3N0M0) tại đơn vị tuyến vú Bệnh viện Chợ Rẫy. VMJ. 2022; 513(2). doi:10.51298/ vmj.v513i2.2493.
7. Nguyễn Đỗ Thùy Giang, Nguyễn Chấn Hùng, Trần Văn Thiệp và cs (2008). Khảo sát tỉ lệ di căn hạch nách trong ung thư vú giai đoạn I‐II. Tạp chí Y Học TP.HCM, tập 12, phụ bản 4, chuyên đề ung bướu học, tr.282‐290.
8. Huỳnh Thị Đỗ Quyên và CS (2014) Giá trị tiên đoán dương các đặc điểm hình ảnh siêu âm hạch nách trên bệnh nhân ung thư vú. Y Học TP. Hồ Chí Minh Tập 18 Phụ bản của Số 1 2014.
9. Whitman GJ, Lu TJ, Adejolu M, Krishnamurthy S, Sheppard D. Lymph Node Sonography.UltrasoundcClinics. 2011; 6(3):369-380. doi:10.1016/j.cult.2011.05.005