KHẢO SÁT ĐẶC ĐIỂM MÔ BỆNH HỌC THÀNH TĨNH MẠCH TINH Ở NGƯỜI BỆNH GIÃN TĨNH MẠCH TINH

Abstract

Purpose: The purpose of this study is to describe the histopathological characteristics of spermatic vein wall in patients with varicocele. Methods: Cross-sectional descriptive study. The study was conducted on 61 patients with varicocele who underwent surgical treatment for varicocele veins constriction from November 2022 to June 2023. During the surgery, a segment of the dilated varicocele veins was collected for pathological examination. Results: All varicocele veins were clinically classified as grade 3. Venous valve defects were found in a high proportion of cases 95.1%, with 59.0% having no valves and 36.1% having structurally abnormal valves. A correlation was found between valve damage and signs of venous reflux on Doppler ultrasound. The average thickness of the tunica media, tunica adventitia and entire varicocele vein wall was 356.3 ± 99.58µm, 103 ± 34.32µm, and 467.6 ± 110.84µm, respectively. The percentage of connective tissue in the tunica media and tunica adventitia was 30 ± 7.32% and 53.5 ± 7.42%, respectively, and a correlation was found between the percentage of connective tissue in the tunica media and the number of constrictions in each varicocele vein. Conclusion: Valve defects in varicocele veins contribute to venous reflux and the development of varicocele pathology. Larger varicocele veins are associated with increased connective tissue proliferation in the tunica media.