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Date Published: 20/02/2024
Abstract Views: 110
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DOI: https://doi.org/10.51298/vmj.v535i2.8514
Issue
Vol. 535 No. 2 (2024)
Section
Các bài báo
How to Cite
Vũ, T. T., Lương, Q. C., Bùi, T. H. G., & Trần, H. T. (2024). STUDYING THE EFFECT OF MECHANICAL VENTILATION STRATEGY ON MORTALITY RATE IN PATIENTS WITH ACUTE RESPIRATORY DISTRESS SYNDROME. Vietnam Medical Journal, 535(2). https://doi.org/10.51298/vmj.v535i2.8514

STUDYING THE EFFECT OF MECHANICAL VENTILATION STRATEGY ON MORTALITY RATE IN PATIENTS WITH ACUTE RESPIRATORY DISTRESS SYNDROME

Thiên Tài Vũ, Quốc Chính Lương, Thị Hương Giang Bùi, Hữu Thông Trần

Main Article Content

Abstract

Objective: Determine the relationship between mechanical ventilation parameters and mortality in patients with acute respiratory distress syndrome. Methods: A cross-sectional descriptive study on 124 patients with progressive acute respiratory failure at Bach Mai Hospital. Data collection and analysis of parameters including: patient characteristics, ventilator settings, and treatment outcomes. Results: The mortality rate was 62.9%. Higher Ppeak, Pplat, and driving pressure were statistically significant in the mortality group. Specifically, driving pressure was an independent predictor of mortality with OR 1.316 (95% CI 1.00 – 1.73), p=0.05. Conclusion: High airway pressure is independently associated with increased mortality in patients with acute respiratory distress syndrome.

Article Details

Keywords

Acute respiratory distress syndrome (ARDS); Mechanical ventilation; Risk factors.

References

1. Matthay MA, Zemans RL. The Acute Respiratory Distress Syndrome: Pathogenesis and Treatment. Annu Rev Pathol Mech Dis. 2011;6(1):147-163. doi:10.1146/annurev-pathol-011110-130158
2. Bellani G, Laffey JG, Pham T, et al. Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries. JAMA. 2016; 315(8):788. doi:10.1001/jama. 2016.0291
3. Slutsky AS, Ranieri VM. Ventilator-Induced Lung Injury. N Engl J Med. 2013;369(22):2126-2136. doi:10.1056/NEJMra1208707
4. Briel M, Meade M, Mercat A, et al. Higher vs Lower Positive End-Expiratory Pressure in Patients With Acute Lung Injury and Acute Respiratory Distress Syndrome: Systematic Review and Meta-analysis. JAMA. 2010;303(9): 865-873. doi:10. 1001/ jama.2010.218
5. Protti A, Andreis DT, Monti M, et al. Lung Stress and Strain During Mechanical Ventilation: Any Difference Between Statics and Dynamics?*. Crit Care Med. 2013;41(4):1046. doi:10.1097/ CCM.0b013e31827417a6
6. Chiumello D, Carlesso E, Brioni M, Cressoni M. Airway driving pressure and lung stress in ARDS patients. Crit Care. 2016;20:276. doi:10.1186/s13054-016-1446-7
7. Marini JJ, Jaber S. Dynamic predictors of VILI risk: beyond the driving pressure. Intensive Care Med. 2016;42(10): 1597-1600. doi: 10.1007/ s00134-016-4534-x
8. Fuller BM, Mohr NM, Drewry AM, Carpenter CR. Lower tidal volume at initiation of mechanical ventilation may reduce progression to acute respiratory distress syndrome: a systematic review. Crit Care Lond Engl. 2013;17(1):R11. doi:10.1186/cc11936