NGHIÊN CỨU KĨ THUẬT CHỤP CẮT LỚP VI TÍNH HAI MỨC NĂNG LƯỢNG TRONG CHẨN ĐOÁN UNG THƯ PHỔI KHÔNG TẾ BÀO NHỎ

Abstract

Objective: To assess the efficacy of spectral computed tomography (CT) imaging parameters for differentiating Research to evaluate the value of the indicators of two-energy level CT scan in diagnosing types of adenocarcinoma and squamous carcinoma in non-small cell lung cancer.  Methods: We conducted a cross-sectional descriptive study in 42 patients with solitary pulmonary nodules proved by pathology underwent double-phase enhanced CT scan at the Diagnostic Imaging Center of K Hospital, Hanoi from March 2022 to February 2023. The slope rate was calculated from the spectral curve. The independent T-test were performed to compare quantitative parameters (IC, nIC, HU slope rate) of pulmonary nodules between squamous cell carcinoma from adenocarcinoma.  Results: The study included 23 non-small cell lung cancer patients (20 men, 3 women). The average age was 57,0 ± 9,9 years. The proportion of patients smoking was 60,9%. Overall, the naIC, vIC, nvIC parameters in adenocarcinoma lesions were 0,25 ± 0,14, 1,60 ± 0,56mg/ml and 0,42 ± 0,14, respectively, were all higher than in squamous carcinoma (were 0,11 ± 0,05, 1,01 ± 0,30 mg/ml and 0,27 ± 0,06, respectively) (all p values <0.05). However, aIC and HU slope rate (lHU) parameters did not have a statistically significant difference between the 2 lesion groups. Conclusion: The parameters naIC, vIC and nvIC derived from enhanced DECT were useful to discriminate squamous cell carcinoma from adenocarcinoma. However, the aIC and lHU parameter has little role in distinguishing these two different pathological types of non-small cell lung cancer