INTRAVENOUS LIPID 20% EMULSION THERAPY IN THE TREATMENT OF ACUTE POISONING

Văn Thực Nguyễn , Hữu Thông Trần, Trần Hưng Hà

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Abstract

Objective: to assess the use of 20% intravenous lipid emulsion (ILE) therapy in the treatment of acute poisoning. Subjects and methods: an observational study included 34 patients with acute poisoning who used ILE from January 2022 to August 2023 at the Poison Control Center of Bach Mai Hospital. Results: ILE therapy was indicated for poisoning of anesthetics, calcium channel blockers, antidepressants and pesticides poisoning; The severity according to PSS: moderate accounted for 29.4%, severe 67.6%, and fatal 2.9%. Indications of ILE were mainly hypotension (38.2%), unconsciousness (29.4%) and cardiac arrest 2.9%. 67.6% of ILE were used immediately in combination with other treatments, 26.5% were salvage therapy. 52.9% of ILE used the correct dose according to the regimen. Conclusion: the study showed the current status of using 20% intravenous lipid emulsion therapy in the treatment of acute poisoning patients at the Poison Control Center of Bach Mai Hospital.

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References

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