TỔNG QUAN LUẬN ĐIỂM CÁC PHƯƠNG PHÁP ĐIỀU TRỊ U NHÚ ĐƯỜNG HÔ HẤP TÁI PHÁT Ở TRẺ EM GIAI ĐOẠN 2013-2022

Abstract

Objective: Analyse the results of several treatments of recurrent respiratory papillomatosis in children in the period 2013-2022. Methods: A scoping review. Results: Out of a total of 295 articles searched on Pubmed database, the Cochrane library, the digital library Ha Noi Medical University, 18 articles on 401 patients with recurrent respiratory papillomatosis in children fit the selection criteria. The results of a review of 18 studies show that in the past 10 years, surgery combined with adjuvant bevacizumab was the most studied, followed by surgery combined with adjuvant vaccines (HPV, mumps), surgery alone and less researcher is surgery combined with adjuvants Acyclovir, Nivonumab, PDT, Cidofovir, Interferon, antihistamine H2… Conclusion: Treatment of recurrent respiratory papillomatosis in children includes many methods in which surgery alone gives the poorer results and a higher recurrence rate than surgery combined with adjuvant therapies. This opens opportunities to form new protocol in management of recurrent respiratory papillomatosis in children.