INVESTIGATION OF THE VALUE OF COMBINING UNILATERAL SINUS LESIONS WITH COMPLETE, HETEROGENEOUS SINUS OPACITIES ON CT-SCANNER IN THE DIAGNOSIS OF FUNGAL SINUSITIS
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Abstract
Purpose: To investigate the value of combining unilateral sinus lesions with complete, heterogeneous sinus opacities on computed tomography (CT) in the diagnosis of fungal sinusitis. Material and methods: Descriptive study on 70 patients with chronic rhinosinusitis examined at Hanoi Medical University Hospital during the period from January 2022 to July 2023. These patients were all had endoscopy and multi-slices CT scan of the sinuses, then had endoscopic sinus surgery and confirmed diagnosis of fungal sinusitis by post-operative fungal testing. Signs of unilateral sinus lesion and complete, heterogeneous sinus opacities on CT were combined together and compared with post-operative fungal testing to investigate the value of combining these two signs. Results: Fungal sinusitis was diagnosed in 60/70 patients, accounting for 86%. On CT scan, the sign of unilateral sinus lesion location had the sensitivity, the specificity, the diagnostic accuracy, the positive predictive value, and the negative predictive value for the diagnosis of fungal sinusitis of 91.7%; 0%; 78.6%; 84.6% and 0%, respectively. These values for the complete, heterogeneous sinus opacities sign were 80%; 20%; 71.4%; 85.7% and 14.3%, respectively. When combining the sign of unilateral sinus lesion location with the sign of complete, heterogeneous sinus opacification, the sensitivity, the specificity, the diagnosis accuracy, the positive predictive value, the negative predictive value of CT scan for fungal sinusitis diagnosis were 70%; 60%; 68.6%; 91.3% and 25%, respectively Conclusion: Combining two signs of unilateral and complete, heterogeneous sinus opacities, although reduced the sensitivity and the diagnostic accuracy but increased the specificity for the diagnosis of fungal sinusitis by CT.
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References
2. Nicolai P, Lombardi D, Tomenzoli D, et al. Fungus ball of the paranasal sinuses: experience in 160 patients treated with endoscopic surgery. Laryngoscope 2009; 119(11):2275–9.
3. deShazo RD, O’Brien M, Chapin K, Soto-Aguilar M, Gardner L, Swain R. A new classification and diagnostic criteria for invasive fungal sinusitis. Arch Otolaryngol Head Neck Surg. 1997;123(11):1181-1188.
4. Aribandi M, McCoy VA et al. Imaging features of invasive and noninvasive fungal sinusitis: a review. Radiogr Rev Publ Radiol Soc N Am Inc. 2007;27(5):1283-1296.
5. Junaid Iqbal et al. Diagnostic Accuracy of CTScan in Diagnosing Paranasal Fungal Infection. Journal of the College of Physicians and Surgeons Pakistan 2017, Vol. 27 (5): 271-274
6. Lê Trung Nguyên. Nghiên Cứu Tình Hình Viêm Xoang Do Nấm Tại BV TMH TP. Hồ Chí Minh Từ Năm 2020-2021. Luận văn Ths. Đại học Y dược TP Hồ Chí Minh; 2021.
7. Mai Quang Hoàn. Khảo Sát Đặc Điểm Lâm Sàng, Cận Lâm Sàng và Điều Trị Viêm Xoang Do Nấm Tại Bệnh Viện Chợ Rẫy. Luận văn Ths. Đại học Y dược TP Hồ Chí Minh; 2018.
8. Jiang RS, Huang WC, Liang KL. Characteristics of Sinus Fungus Ball: A Unique Form of Rhinosinusitis. Clin Med Insights Ear Nose Throat. 2018;11:1179550618792254.
9. Dufour X, Kauffmann-Lacroix C, Ferrie JC, Goujon JM, Rodier MH, Klossek JM. Paranasal sinus fungus ball: epidemiology, clinical features and diagnosis. A retrospective analysis of 173 cases from a single medical center in France, 1989–2002. Med Mycol. 2006;44(1):61-67.
10. Lê Đức Đông. Nghiên Cứu Đặc Điểm Lâm Sàng, Cận Lâm Sàng và Đánh Giá Kết Quả Điều Trị Của Viêm Mũi Xoang Do Nấm. luận văn CK cấp II. Đại học Y Hà Nội; 2019.