NGHIÊN CỨU MỐI LIÊN QUAN GIỮA NỒNG ĐỘ NT-PROBNP HUYẾT TƯƠNG VỚI MỘT SỐ ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG Ở BỆNH NHÂN NHỒI MÁU CƠ TIM CẤP

Abstract

Objectives: To investigate the relation between plasma NT-proBNP levels at admission with some clinical, subclinical characteristics in patients with acute myocardial infarction. Subjects and methods: A prospective, descriptive and cross-sectional study was conducted on 57 patients with acute myocardial infarction, treated in Cardiovascular Center of Military Hospital 103, from September 2019 to May 2020. The patients underwent clinical examination, laboratory tests, ECG, echocardiography, coronary angiogram and were tested plasma NT-proBNP levels at admission. Results: Mean NT-proBNP levels was 1681,5 ±3846,8 pg/ml, median value was 293,7 pg/ml. There was no difference in  NT-proBNP levels in patients with STEMI and NSTEMI. NT-proBNP levels had a close positive correlation with age (r=0,5, p<0,01), a close positive correlation with Troponin I levels (r=0,5, p<0,01), a slight positive correlation with CK-MB levels (r=0,2, p<0,01) and a moderate correlation with GRACE score (r=0,346, p<0,01). There was no difference in  NT-proBNP levels in patients with different culprit coronary arteries. Conclusion: Plasma NT-proBNP levels in patients with acute myocardial infarction had a close positive correlation with ages and Troponin I levels, a moderate correlation with GRACE score and a slight positive correlation with CK-MB levels.