STUDY OF THE ANTIBIOTICS RESISTANCE SITUATION IN PATIENTS TREATED AT NIHBT DURING PERIOD 2019-2021

Quốc Khánh Bạch , Thị Vân Nga Bùi , Hà Thanh Nguyễn, Đức Bình Vũ

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Abstract

Background: Septicemia is a severe condition commonly seen in patients with blood diseases with immunodeficiency. Purpose: this study aimed to establish the antibiotics resistance in septicemia caused by bacteria and fungi in patients treated at the NIHBT. Patients and methods: 2786 bacteria strands identified from 32.201 positive blood samples of septicemia at NIHBT during period 12/2018-11/2021. Results: (1) Gram negative bacteria have highest antibiotics resistance to ampicillin (>90%), and lower resistance (<5%) to amikacin, fosphomycin; carbapenems (meropenem, imipenem) have 21% resistance; (2) Gram positive bacteria have highest resistance to penicillins (penicillin 81.3%, oxacillin 77.9%), low resistance to vancomycin 1.1%, and linezolid 0.9%; (3) Fluconazole has the highest resistance 40.2%, amphotericin, caspofungin, micafungin have lower resistance (0.4%, 0.9%, 0.4% respectively).  

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References

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