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Date Published: 15/03/2024
Abstract Views: 116
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DOI: https://doi.org/10.51298/vmj.v536i1B.8750
Issue
Vol. 536 No. 1B (2024)
Section
Các bài báo
How to Cite
Nguyễn , T. D., Cấn, X. H. ., Nguyễn , T. L., & Đặng , T. L. . (2024). EVALUATE SURVIVAL TIME OF STAGE IV NON- SMALL CELL LUNG CANCER PATIENTS TREATED BY PEMBROLIZUMAB COMBINED WITH CHEMOTHERAPY AT NATIONAL LUNG HOSPITAL. Vietnam Medical Journal, 536(1B). https://doi.org/10.51298/vmj.v536i1B.8750

EVALUATE SURVIVAL TIME OF STAGE IV NON- SMALL CELL LUNG CANCER PATIENTS TREATED BY PEMBROLIZUMAB COMBINED WITH CHEMOTHERAPY AT NATIONAL LUNG HOSPITAL

Thanh Dương Nguyễn , Xuân Hạnh Cấn, Thành Lâm Nguyễn , Thùy Linh Đặng

Main Article Content

Abstract

Objective: Evaluation of survival time in patients with stage IV non-small cell lung cancer treated with Pembrolizumab regimen combined with chemotherapy. Methods: Cross-sectional descriptive study combined with retrospective with longitudinal follow-up on 63 patients with stage IV non-small cell lung cancer treated with Pembrolizumab regimen combined with chemotherapy at the National Lung Hospital. Implementation period is from June 2019 to June 2023. Results: Patients with stage IV non-small cell lung cancer treated with the Pembrolizumab regimen combined with chemotherapy had a median progression-free survival of 10.91 ± 2.22 months (95%CI: 6.52-15.30). The progression-free survival time between the group with PD-L1 expression was higher than the group without PD-L1 expression, this difference was statistically significant with p = 0.04 < 0.05. Conclusion: Pembrolizumab regimen combined with chemotherapy improves survival time in patients with stage IV non-small cell lung cancer.

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References

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